Podmajersky leads a rebuilding Middletown South softball team

first_img Middletown South A lli Podmajersky, who has complemented Allison Nolan, will lead the way on the mound this season as Middletown High School South’s rebuilding softball team will look to continue its success of past seasons.“We have a young team, and we’re inexperienced against pressure and being in those positions,” said coach Tom Erbig, who brings a 651-201-1 career record over 32 seasons, all but one at Middletown South. (The first one was a 17-11 record at Allentown High School.)Middletown South opens its season on April 1 at Middletown High School North.Podmajersky is part of a nucleus that will look to carry the hitting, along with veterans Abbey Schultz, a senior third baseman who has been batting cleanup, and juniors Grace Heller in center field and Veronica Zega at catcher.They’ll look to help settle the Eagles by filling the gaping holes left by Nolan, who graduated and is now at Rowan University; second baseman Alex Giacinto, who is at Lafayette College; first baseman Erica Falvey, who is at George Mason University; and right fielder Taylor Landis, who is running on the track-and-field team at Caldwell College.“It’s really hard filling those shoes,” Erbig said. “It’s just a different product. We’re younger, smaller and inexperienced, but the players have been working hard.”Sophomore Alex Corrigan, who goes from left field to shortstop, senior Megan Mittzenzwei, who is playing at first base, and senior Karinne Kely, who plays at second base and third base, will bring in some experience from last year’s 21-6 team. Last year, Middletown South saw its season end with a 1-0 loss to East Brunswick High School in the NJSIAA Central Jersey Group IV championship game. Corrigan played some innings at shortstop last season.Middletown South, a perennial section finalist in Group IV, moves into Group III this season, but Erbig said it makes no difference. The only thing that falls to Middletown South’s advantage is that most teams in Shore Conference A North, which it won again last season, are Group IV schools. That will help the Eagles get a good seed based on the power-points system. “We’re getting good, solid pitching from Podmajersky. The only thing suspect right now is our offense,” Erbig said, as Podmajersky throws a wide variety of pitches, including a screwball, fastball, riser and changeup.That was an issue with the Eagles last season. And when they did hit, it sometimes was not timely. In a 4-3 Monmouth County Tournament championship game loss to St. John Vianney High School, a perennial showdown between those two teams in the tournament finals, the Eagles had a 9-3 edge in hits. Middletown South also lost its Shore Conference Tournament opener to Manalapan High School.“We couldn’t capitalize and get big hit — the same thing as all year long,” Erbig said after the EastBrunswick loss. “We had a couple of hits squandered at times in some big games. In general, we didn’t blow games open when we had the opportunities.”Erbig said that remains a concern at this juncture as well. He also has been working at improving the team’s base-running, which was a problem last season.Erbig has plenty of prospects from the sophomore class that were regarded last year as the strongest incoming freshmen class in many years at the school — perhaps ever. From that group, outfielder Julian Bell is hitting well enough to earn ample innings and maybe a starting spot. Tiffani Lambert pitched very well when she took the mound in limited action last season, particularly a Monmouth County Tournament semifinals victory over Allentown the night before the championship loss to St. John Vianney.“The thing I like about this group is that they’re young but trying to do what we’re instructing them to do,” Erbig said. “They’re trying to learn the fine points and get rid of the flaws. They’re working to be better at everything they do, and they’re getting there.”Taylor Dreuer (outfield) and Erin Cotterell (second base) could also help.Junior Elizabeth Gulino adds to the depth in the outfield.Junior Hannah Milano, who transferred from St. John Vianney, could be the designated player. She can also play catcher and first base. Phoneix Starick can play second base or in the outfield.That versatility could help the Eagles if they go deep into the season again and some players may be battling slumps. BY WAYNE WITKOWSKI Correspondent last_img read more

Government has no economic nous

first_imgThe debate on one of the most contentious Budgets concluded on Friday; and unfortunately, more heat than light was generated from the Government benches about where we are headed. While boasting about its plan to spend over $300 billion, the Budget is a patchwork of short-term quick fixes like plaster to cover erupting sores. In developing economies such as ours, however, the Government should be playing a very active role in promoting economic development; and fiscal policy, as executed through its Budget, is the instrument it must use.From our perspective, the greatest failure of Budget 2019 is that it is not guided by a clear strategy to address the challenges that confront Guyanese society today; and inevitably, it therefore lacks coherence in its proposals and projects. Take, for instance, the PNC-led Government’s stated commitment to deliver reliable electricity at lower costs, to encourage the economy to engage in more value-added production and move us away from being a primary-product- price-taking economy.Entering into the fourth and penultimate year before the 2020 elections, the Government is nowhere closer to fulfilling that promise by investing in new generation equipment – whether “green” or “black” — and yet castigates the business community for not investing more. The much touted 25MW wind farm from 2015 has not materialised, and the solar alternatives to the rejected Amaila Falls Hydro-Electric Project (AFHEP) are as still-born as is the “Green State Development Strategy” (GSDS) — which is not even a pale imitation of the world-recognised Low Carbon Development Strategy (LCDS) of the predecessor PPPC regime.What we have dangling under our noses is a nebulous plan to build a 200MW gas-fired generation plant even though Exxon, which is supposed to be producing the natural gas by separating it from oil aboard its Floating Production and Storage Offloading vessel, is recommending that the gas be reinjected to bring up more oil. Guyana has no way of countering the study which is being conducted by Exxon, since it does not have access to the data on which it will be based. Furthermore, a 200MW generation plant – with its liquefaction and regassification plants — will conservatively cost US$500 million, and the Government has not even broached the matter of a feasibility plan for this elephant in the room.Another area in which the PNC Government has exposed its total inability to generate growth is on completing the infrastructural projects they inherited from the PPP. The expansion of the Cheddi Jagan International Airport (CJIA), for instance, was predicated on promoting Guyana as a regional air hub. Unfortunately, the Government has allowed itself to be bamboozled into accepting a severe truncation of the initial plan – a refurbished rather than a new arrivals building, and four rather than eight elevated boarding gates — while spending millions more. The delays on initiating the East Bank-East Coast bypass road and the Lethem-Linden Highway are just two other instances of infrastructural constipation.Another example of the lack of coherence in the budget can be seen from the Government’s refusal to follow up on its manifesto promise to “prepare a long term National Development Plan with consequential programmes based on consultation with relevant bodies and key stakeholders. The objective would be to take sustainable advantage of the vast potential of Guyana’s resource endowments.”Once again, the aforementioned GSDS was touted by the Finance Minister, but without it being tabled in the National Assembly, it is just “ole talk”. In the absence of such a plan, the budget inevitably becomes manifestly an exercise in “ad hocism”, especially when it comes to the economic development of the country. As the Opposition Leader has pointed out, the GSDS is not geared at producing revenues for Guyana’s development, but focuses on spending from the Consolidated Fund. It is clear the PNC Government believes that a “Green State” means painting everything not moving green, to join our pristine forests which are already green.Budget 2019 was an incoherent, missed opportunity, and betrays the PNC Government’s lack of economic nous.last_img read more

Public Health Ministry tackles NCDs

first_imgIn light of deaths caused by Non-Communicable Diseases (NCDs), The Public Health Ministry has intensified efforts to reduce the number of deaths caused by these illnesses annually.Based on statistics, NCDs account for 70 per cent of all deaths in Guyana and is the number one cause of premature deaths (before the age of 70 years).The Ministry said in a statement that Guyana’s main NCDs – cardiovascular diseases, diabetes, cancer and chronic respiratory disease – account for the highest burden on mortality and morbidity.It contended that these diseases are totally preventable by the simple modification of four risk factors: harmful tobacco use, unhealthy diet, physical inactivity and harmful use of alcohol.The Ministry’s Chronic Disease Unit in its efforts to combat NCDs will be conducting a STEP-wise approach population based survey from July to October, 2016, to determine chronic disease risk factors and surveillance in Guyana.“The listing process is scheduled to commence on Thursday, July 14 and will conclude on Monday, July 18, 2016,” the Ministry said, adding “for many years, Guyana has been utilising estimated statistics to account for the population at risk of developing NCDs and for those who are already living with these diseases. This approach will now be changed.”The release added that upon the completion of the STEPS survey, statistics will be acquired and Guyana will now have baseline figures which will allow health officials to closely monitor the population, which will facilitate the development and implementation of appropriate interventions to treat and prevent chronic non-communicable diseases.The survey will also give the Public Health Ministry a better chance to be able to properly forecast and procure the right type of medications and in its sufficient quantities, hence preventing drug shortages in the country.The STEPS survey is a voluntary survey and all participants will be notified of their results at the end of the assessment, the Ministry assured.A total of 3456 households will be randomly chosen to participate in the STEPS survey. One person (within the household) between the ages of 18 to 69 years will be asked to participate in an interview.The participants will be required to respond to basic questions pertaining to demographics, habits and lifestyle practices as it relates to the risk factors of NCDs – have their weight; height and blood pressure checked and recorded by the officer conducting the survey; and give a small blood sample to be tested for blood sugar, cholesterol, sickle cell and thalassemia, which are two common blood disorders found in Guyana.The Public Health Ministry will be collaborating with the Bureau of Statistics in executing the STEPS survey. The Bureau will be carrying out the listing process, which entails trained personnel visiting communities to map out the layout of houses, after which the households will be randomly selected.The Ministry is pleading with communities to support the initiative.last_img read more

ON THIS DAY: Chelsea sign Gianfranco Zola – WATCH his backheel goal here!

first_imgOne of the best players to ever appear in the Premier League arrived on these shores on this date in 1996, when Chelsea completed the deal to bring Gianfranco Zola to Stamford Bridge.The Italian wizard signed for £4.5million from Parma – a relative bargain given how he propelled Chelsea to the top of the English game.The Blues’ trophy drought ended when Zola arrived in West London, with them winning two FA Cups, a League Cup, a Charity Shield, the UEFA Cup Winners’ Cup and the UEFA Super Cup with the Italian spearheading their attack.He left in the summer of 2003 to join Cagliari in his homeland of Sardinia, just before Roman Abramovich bought the club, and it has been rumoured that Abramovich tried to buy Cagliari as well to convince Zola to stay at Stamford Bridge.Zola is a club icon, and one of the most important players in the history of Chelsea, and to celebrate the day he arrived in England talkSPORT present you with the chance to relive one of his greatest ever goals.Watch the video of his backheel goal against Norwich above to remember just how good Zola actually was, on this important day in football history…last_img read more

Manchester City transfer news: Bruno Zuculini makes Hellas Verona switch

first_img1 Manchester City midfielder Bruno Zuculini has joined Hellas Verona on loan for the rest of the season, linking up with his brother Franco at the Serie B leadersThe 23-year-old Argentinian has yet to make a league appearance for City since joining in 2014 from Racing Club and has spent the interim period on a succession of loan deals, including stints at Valencia, Middlesbrough and AEK Athens.The Argentinian moved to Rayo Vallecano on a season-long loan last November but, after making nine appearances for the Spanish second division side, he has now moved to Italy.A Verona statement read: “Hellas Verona announces the loan signing of Bruno Zuculini from Manchester City. The midfielder has completed his medical and has already trained with the club, thanks to the willingness of Manchester City and Rayo Vallecano.” Zuculini has yet to make a league appearance for the Citizens last_img read more

Everton plot ‘substantial’ Zaha bid, but Simon Jordan warns him off

first_img targets moving on 2 Everton are considering making a ‘substantial’ bid for Crystal Palace winger Wilfried Zaha, according to talkSPORT sources.The 26-year-old has been linked with a switch to Arsenal all summer, although the Gunners are yet to table an offer that comes anywhere close to the Eagles’ £80million valuation. However, talkSPORT host Jim White – who has close ties with Everton’s majority shareholder Farhad Moshiri – claims the Toffees have now entered the race for Zaha. Liverpool’s signings under Michael Edwards – will Minamino be the next big hit? targets Where every Premier League club needs to strengthen in January “He’s ultimately not going to achieve that at Arsenal either [this season], but with the greatest will in the world, I just think there are a lot more components for him to go to Arsenal than to go to Everton.“He’s a London boy and I think he likes the idea of staying in London. getty The biggest market value losers in 2019, including Bale and ex-Liverpool star LIVING THE DREAM Chelsea confident of beating Man United and Liverpool to Sancho signing Tony Cascarino backs Everton to sign two strikers for Carlo Ancelotti three-way race TOP WORK center_img 2 LATEST TRANSFER NEWS AND GOSSIP Everton are planning to rivals Arsenal in the race to sign Wilfried Zaha from Crystal Palace According to @talkSPORT sources, don’t rule out @Everton making a substantial bid for Wilfried Zaha.— Jim White (@JimWhite) July 24, 2019Moshiri is reportedly keen to make and willing to finance a ‘statement signing’ before the summer transfer window shuts, having previously been linked with former Chelsea striker Diego Costa.Meanwhile, with Adamola Lookman set to join German club RB Leipzig, manager Marco Silva is said to be in the market for another winger and also wants to boost his team’s goal scoring ability.Lille forward Nicolas Pepe has been linked with a move to Goodison and now his Ivory Coast team-mate Zaha is wanted by the Merseyside club. However, former Crystal Palace chairman Simon Jordan believes it would be the wrong move for the Eagles star.Zaha has made it clear he wants to leave Selhurst Park to play Champions League football, and Jordan doubts whether he and Everton are the right fit.Speaking to Jim White on Wednesday, Jordan said: “They’ve not a Champions League contender at this moment in time, and I know Everton fans will be up in arms and say, ‘we will be soon enough’.“Zaha has explicitly talked about wanting to play in the Champions League. Arsenal transfer news LIVE: Ndidi bid, targets named, Ozil is ‘skiving little git’ REVEALED LATEST getty Kevin De Bruyne ‘loves Man City and wants to keep winning’, reveals father Video Player is loading.Play VideoPlayMuteCurrent Time 0:00/Duration 0:12Loaded: 98.22%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -0:12 Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedCaptionscaptions settings, opens captions settings dialogcaptions off, selectedAudio Tracken (Main), selectedFullscreenThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window.Close Modal DialogThis is a modal window. This modal can be closed by pressing the Escape key or activating the close button.PlayMuteCurrent Time 0:00/Duration 0:00Loaded: 0%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -0:00 Playback Rate1xFullscreen Zaha has publicly said he wants to play Champions League football Cavani ‘agrees’ to join new club and will complete free transfer next summer Wilfried Zaha always wanted to join Arsenal and has supported the club from a young age “Going up north to Everton, whilst being a great football club, is a departure into an area he’s been before at a different stage of his life at Manchester United.“He’s spoken openly about wanting to play for Arsenal and the style of football Arsenal bring to the table.“But money will talk in the end.”last_img read more

All about the African Union

first_imgIn 1963 the Organisation of African Unity rose from the ashes of colonial rule. Since then, as the African Union, it has expanded and embraced its ever-growing role. The opening ceremony of the 23rd Ordinary Session of the Assembly of the African Union in Malabo, Equatorial Guinea, on 26 June 2014. (Image: AU Facebook) Priya PitamberAs African countries shook off the shackles of their colonial masters and gained their independence in the 1950s and 1960s, they recognised the need for a unified voice on the continent.This led to the formation of the Organisation of African Unity (OAU), which officially came into being on 25 May 1963 in Addis Ababa, Ethiopia. At inception, it comprised 32 independent African states; over the years, the number of member states gradually increased.However, Morocco withdrew its membership in 1984. Then, in the 1990s, OAU leaders debated an alternative structure for the organisation in response to the rapidly changing global political environment. By 1999, the OAU heads of state and government had issued the Sirte Declaration to establish a new African Union (AU). The AU was launched in Durban, South Africa in 2002, when it convened its first meeting.On 9 July 2011, South Sudan joined the AU, becoming the 54th country to do so.See images of the launch in 1963:The Heads of African States and Governments have signed the OAU Charter in the City of Addis Ababa, Ethiopia, 25th day of May, 1963Posted by African Union on Thursday, 16 May 2013 Addis Ababa, May 1963. for the first time in history, the leaders and representatives of all independent African states meet under one roof.Posted by African Union on Thursday, 16 May 2013The official languages of the AU are diverse: Arabic, English, French, Kiswahili, Portuguese, Spanish, and any other African language, but the working languages are limited to Arabic, English, French and Portuguese.Basic structureThere are various organs within the AU:The AssemblyThis is made up of the heads of state and government or their ascribed representatives. It is the highest structure in the AU.The Executive CouncilThe Executive Council is composed of ministers or authorities chosen by the governments of member states. They are accountable to the Assembly.The CommissionsEach commission has a specified portfolio and is made of a chairperson, a deputy chairperson, eight commissioners and other staff members.The Permanent Representatives’ CommitteeThis committee comprises permanent representatives of member states accredited to the AU. It is responsible for executing the work of the Executive Council and Assembly.The Peace and Security CouncilThe Peace and Security Council (PSC) was set up to provide quick and efficient responses to crises. It is made up of 15 members.The Pan-African ParliamentThe purpose of the Pan-African Parliament, or PAP, is to “ensure the full participation of African peoples in the development and economic integration of the continent”. It has up to 250 members representing the 54 AU member states.There are also numerous other organs within the AU, which deal with judicial, legalisation, financial, economic, and human rights issues.Role of the unionMany of the core principals of the OAU moved over to the AU:• To promote the unity and solidarity of African states;• To co-ordinate and intensify their co-operation and efforts to achieve a better life for the peoples of Africa;• To safeguard the sovereignty and territorial integrity of member states;• To promote international co-operation within the UN framework; and,• To harmonise members’ political, diplomatic, economic, educational, cultural, health, welfare, scientific, technical and defence policies.Watch the opening of the 24th Ordinary Session of the AU Assembly, which took place on 30 January this year in Addis Ababa, the seat of the union:Sources:AU Handbook 2015 and the AU website.last_img read more

Barnes & Noble.com Re-Designed: Adds Some Web 2.0 Elements, But Still Far Behind Amazon.com

first_imgTop Reasons to Go With Managed WordPress Hosting Why Tech Companies Need Simpler Terms of Servic… Tags:#news#web richard macmanus A Web Developer’s New Best Friend is the AI Wai… Joe Wikert has a nice review of the re-design, noting that it is “disappointing to see that B&N’s page has nothing to offer on the widget front.” Indeed check our recent review of Random House’s widget and web services program to see what B&N could have done. Wikert also says it is light on customization options.Barnes&Noble has a long way to go to catch up with Amazon.com, the online book store market leader – in both sales and innovation. Also Borders recently announced a beta design, which Joe Wikert has info on (I found a great new feed tonight, subscribed Joe!).Overall, a lot of nice new functionality in the new B&N – but it’s still far from Amazon.com’s level. No recommendation technology, no widgets, no web services, no RSS, little customization. Still, it has some nice multimedia and uses many of the UI elements popularized by Amazon.com (e.g. wishlists). Its current user base will be pleased, although there doesn’t seem to be much to attract new users. Barnes & Noble.com has launched a re-design, with several new web 2.0 features – including “One on One” podcasts, a large tag cloud on the frontpage, a “See Inside” program that offers a virtual book-reading like experience, and a service called “Live at Barnes & Noble” where you can view webcasts of readings at member stores. Another new feature is B&N Review, a daily magazine with reviews and interviews.The goal of the re-design was to add more “motion”, as well as more content, interactivity, and community. The AP report also noted that Barnes & Noble.com “has become increasingly important to Barnes & Noble Inc. […] The online seller’s percentage of the superstore’s total sales have doubled in the past five years to 10 percent.” Related Posts 8 Best WordPress Hosting Solutions on the Marketlast_img read more

Facebook Lets You Write In Whatever Gender You Want

first_imgFacebook is Becoming Less Personal and More Pro… Related Posts Guide to Performing Bulk Email Verification Thursday, Facebook announced the addition of a free-form field to the Gender options area in Facebook profiles. The new “custom” option space allows users to write in any description they want—whether “dog-loving master of bro-associated domains” or “cheese-eating king.” Facebook explains the change in a post on the Facebook Diversity Page, noting that if you don’t identify with available gender identities offered, you can add your own. People “can add up to ten gender terms and also have the ability to control the audience with whom you would like to share you custom gender,” the company wrote. See also: Facebook Provides 56 New Gender Identity OptionsThe post suggests the custom field joins the drop-down list of 56 different gender options Facebook introduced last year. But when we checked it out, that drop-down no longer appears, indicating it replaced the hefty list. Perhaps it’s all for the best. Who would go with a canned description when you could be a “couch-surfing artist sloth”? The move may finally please critics, particularly folks who have been clamoring for the right to describe themselves however they want. Saving FaceFacebook made its first big change to the Gender section of users’ About page after Olu George posted a complaint in the company’s help center last year: “As someone who doesn’t identify with female or male pronouns, I feel like FB is excluding people. FB needs to create another option for people who identify as genderqueer/two spirit/transgender etc.” George suggested that FB change its gender options to Male, Female and Other: Genderqueer/Two Spirit/Trans. Facebook responded with more than just an “other” option. The company crammed in dozens of possibilities, including genderqueer, intersex, pangender, trans, transsexual and two-spirit. Now, with the latest ability for write-in designations, gender identification on Facebook opens up more flexibility and maybe even a playful fluidity. Mine now reads as “I am gender: ‘pink cat baby owl blue flowers dog bowl furball’ but prefer pronoun ‘She’.” To change your gender description, log into your Facebook profile, hit the “update info” button, go to “contact and basic info” and scroll down to the gender section. Under “Male” and “Female,” there’s a new “Custom” option.You can change your gender description or preferred pronoun whenever they want—Facebook does not lock people into what they’ve chosen on any given day. Facing RealityAs great a tool as it could be for self-expression, the custom gender field could also come with some down sides. Facebook seemingly acknowledges the fluidity in the way some people identify their genders. Instead of forcing fixed labels, people can fill in whatever they want. (Though the company contradicts itself by only offering three pronouns: He, She, and They.) But the move could open up fluidity of another kind as well. On the other hand, fill-in-the-blank genders could also turn into an Internet joke or, at its worst, even a tool for prejudice. Imagine coming across a profile and seeing someone identify as a homo-bashing super-hater. The Internet is rife with trolls, some of whom will use anything they can to spread their vitriol. See also: Your Twitter Gender Is Probably Male, Even If You’re FemaleBut a bigger question remains: Can we trust Facebook to handle those issues, some of which will almost certainly crop up. And if the complexities prove too challenging to deal with, will it back-pedal once again and remove the field? Facebook has not shown the deftest of hands in dealing with complex matters. The company’s ill-advised “crackdown” on pseudonyms used by drag queens kicked up quite a fuss in the LGBTQ community, which was incensed by the so-called “real name” policy. Facebook reversed its decision, but it’s unclear if the network will know how to provide a safe place for people to express non-normative self-identifiers. [Update: I contacted Facebook to seek clarity around the real names policy. A spokesperson responded: “The policy has not been changed, but for the last six months Facebook has been working to enhance the way the policy is enforced.” Facebook now provides a third option for people who want to verify the names they use on Facebook, which includes showing two forms of ID from Option 2 (non-government ID name verification) and a government ID that includes a date of birth or photo that matches information on the profile. With this option, Facebook will not add the name or other information from the government ID to the account.]Lead photo by evan courtney; Facebook photo and screencaps by Alicia Eler for ReadWrite The Dos and Don’ts of Brand Awareness Videoscenter_img A Comprehensive Guide to a Content Audit Tags:#Facebook#Gender#social networking alicia elerlast_img read more

Reelin’ in Clues to Schizophrenia

first_imgPeople with schizophrenia have abnormally low levels of a protein called reelin in the brain. Now researchers have found that this protein seems to play an important role in guiding newborn neurons to their final homes. They suggest that a lack of this protein could lead to schizophrenia by impoverishing neural circuits important for normal cognition–although they and other researchers caution that this mechanism is still speculative.Researchers knew that reelin plays an important role in brain development because mice that lack the reelin gene have a misshapen cerebral cortex and a peculiar gait (thus the nickname “reeler” mice). They also knew that some psychiatric patients, including schizophrenics, have abnormally low levels of reelin. But scientists have had a hard time figuring out exactly what reelin does.Preliminary experiments suggested to Kiminobu Sugaya, of the University of Illinois, Chicago, that reelin might help guide new neurons to the correct location in the brain. To test this, he and colleagues injected human neural stem cells into the brains of normal mice and reeler mice. A month later they looked at the brains under a microscope. In the normal mice, the introduced cells had migrated to the hippocampus and cortex, areas critical for cognitive functions such as learning and memory. But in reeler mice, the implanted cells failed to migrate, the team reports in the 19 March issue of the Proceedings of the National Academy of Sciences. Sugaya’s team also found evidence that reelin guides the migration of the mice’s own stem cells: When they injected mice with a compound that labels newborn cells, they found far fewer new neurons in the hippocampus and cortex of reeler mice. A reelin deficiency–like that seen in schizophrenics–could prevent new-formed neurons from migrating properly and integrating themselves into brain circuits, the team concludes.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)The study “adds to the evidence that reelin may be important for neural cell migration,” says Lalit Srivastava, a psychiatrist at McGill University in Toronto. But Gabriella D’Arcangelo of Baylor College of Medicine in Houston, who discovered reelin in 1995, says that Sugaya’s evidence that the mice’s own stem cells migrate to the cortex isn’t conclusive and warns that the link between reelin and schizophrenia is still speculative.Related linksSugaya’s siteSchizophrenia information from the National Institutes of Health Information about reelinlast_img read more